• Well developed deformation in Si42
    with S. Takeuchi, M. Matsushita, N. Aoi, P. Doornenbal, K. Li, T. Motobayashi, H. Scheit, D. Steppenbeck, H. Wang, H. Baba, D. Bazin, L. Càceres, H. Crawford, P. Fallon, R. Gernhäuser, J. Gibelin, S. Go, S. Grévy, C. Hinke, C. R. Hoffman, R. Hughes, E. Ideguchi, D. Jenkins, N. Kobayashi, Y. Kondo, R. Krücken, T. Le Bleis, G. Lee, A. Matta, S. Michimasa, T. Nakamura, S. Ota, M. Petri, T. Sako, H. Sakurai, S. Shimoura, K. Steiger, K. Takahashi, M. Takechi, Y. Togano, R. Winkler, and K. Yoneda
    Excited states in Si38,40,42 nuclei have been studied via in-beam γ-ray spectroscopy with multinucleon removal reactions. Intense radioactive beams of S40 and S44 provided at the new facility of the RIKEN Radioactive Isotope Beam Factory enabled γ-γ coincidence measurements. A prominent γ line observed with an energy of 742 keV in Si42 confirms the 2 + state reported in an earlier study. Among the γ lines observed in coincidence with the 2 +→0 + transition, the most probable candidate for the tr…Read more
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    We present noninvasive, quantitative in vivo measurements of methemoglobin formation and reduction in a rabbit model using broadband diffuse optical spectroscopy. Broadband DOS combines multifrequency frequency-domain photon migration with time-independent near infrared spectroscopy to quantitatively measure bulk tissue absorption and scattering spectra between 600 nm and 1,000 nm. Tissue concentrations of methemoglobin, deoxyhemoglobin, and oxyhemoglobin were determined from absorption spectra …Read more
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    Androgen receptor and chemokine receptors 4 and 7 form a signaling axis to regulate CXCL12-dependent cellular motility
    with J. J. Hsiao, B. H. Ng, M. M. Smits, J. Wang, R. J. Jasavala, H. D. Martinez, J. J. Alston, H. Misonou, J. S. Trimmer, and M. E. Wright
    © Hsiao et al.; licensee BioMed Central.Background: Identifying cellular signaling pathways that become corrupted in the presence of androgens that increase the metastatic potential of organ-confined tumor cells is critical to devising strategies capable of attenuating the metastatic progression of hormone-naïve, organ-confined tumors. In localized prostate cancers, gene fusions that place ETS-family transcription factors under the control of androgens drive gene expression programs that increas…Read more
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    Treating insomnia improves mood state, sleep, and functioning in bipolar disorder: A pilot randomized controlled trial
    with A. G. Harvey, A. M. Soehner, K. A. Kaplan, K. Hein, J. Kanady, D. Li, S. Rabe-Hesketh, T. A. Ketter, T. C. Neylan, and D. J. Buysse
    © 2015 American Psychological Association.Objective: To determine if a treatment for interepisode bipolar disorder I patients with insomnia improves mood state, sleep, and functioning. Method: Alongside psychiatric care, interepisode bipolar disorder I participants with insomnia were randomly allocated to a bipolar disorder-specific modification of cognitive behavior therapy for insomnia or psychoeducation as a comparison condition. Outcomes were assessed at baseline, the end of 8 sessions of tr…Read more
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    Epigenetic Regulation of Phosphodiesterases 2A and 3A Underlies Compromised β-Adrenergic Signaling in an iPSC Model of Dilated Cardiomyopathy (review)
    with H. Wu, L. G. Vincent, Q. Wang, M. Gu, F. Lan, J. M. Churko, K. I. Sallam, E. Matsa, A. Sharma, J. D. Gold, A. J. Engler, Y. K. Xiang, D. M. Bers, and J. C. Wu
    © 2015 Elsevier Inc. β-adrenergic signaling pathways mediate key aspects of cardiac function. Its dysregulation is associated with a range of cardiac diseases, including dilated cardiomyopathy. Previously, we established an iPSC model of familial DCM from patients with a mutation in TNNT2, a sarcomeric protein. Here, we found that the β-adrenergic agonist isoproterenol induced mature β-adrenergic signaling in iPSC-derived cardiomyocytes but that this pathway was blunted in DCM iPSC-CMs. Although…Read more
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    From Puzzle to Progress: How Engaging With Neurodiversity Can Improve Cognitive Science
    with Marie A. R. Manalili, Amy Pearson, Justin Sulik, Louise Creechan, Mahmoud Elsherif, Inika Murkumbi, Flavio Azevedo, Kathryn L. Bonnen, Judy S. Kim, Konrad Kording, Manifold Obscura, Steven K. Kapp, Jan P. Röer, and Talia Morstead
    Cognitive Science 47 (2). 2023.
    In cognitive science, there is a tacit norm that phenomena such as cultural variation or synaesthesia are worthy examples of cognitive diversity that contribute to a better understanding of cognition, but that other forms of cognitive diversity (e.g., autism, attention deficit hyperactivity disorder/ADHD, and dyslexia) are primarily interesting only as examples of deficit, dysfunction, or impairment. This status quo is dehumanizing and holds back much-needed research. In contrast, the neurodiver…Read more
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    © 2016, UNESCO IBE.Using comparative data, this article examines the level and distribution of participation in adult education opportunities among countries that participated in PIAAC. It considers observed cross-country patterns in relation to some mechanisms that drive unequal chances to participate and to some policy issues that surround the provision, governance, and financing of different types of adult learning. It also explores recent policy developments relevant to AE in three selected …Read more