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55Cyclin-dependent kinase 5 has been implicated in Alzheimer's disease pathogenesis. Here, we demonstrate that overexpression of p25, an activator of cdk5, led to increased levels of BACE1 mRNA and protein in vitro and in vivo. A p25/cdk5 responsive region containing multiple sites for signal transducer and activator of transcription was identified in the BACE1 promoter. STAT3 interacts with the BACE1 promoter, and p25-overexpressing mice had elevated levels of pSTAT3 and BACE1, whereas cdk5-defic…Read more
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21Dc-bias-field-induced dielectric relaxation and ac conduction in CaCu3Ti4O12ceramicsPhilosophical Magazine 88 (4): 537-545. 2008.
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3Flashpoint epistemology (edited book)Routledge. 2023.The 21st century is steeped in claims to interconnection, technological innovation, and new affective intensities amid challenges to the primacy and centrality of 'the human'. Flashpoint epistemology attends to the lived difficulties that arise in teaching, policymaking, curriculum and research among continuous practices of differentiation, and for which there is no pre-existing template for judgment, resolution or action. Flashpoint Epistemology Volume 1 examines contemporary collisions and rew…Read more
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9Coevolution of Strategy, Innovation and EthicsJournal of Business Ethics 186 (4): 711-721. 2023.The way in which business ethics change over time will remain theoretically unclear unless we empirically reveal the temporal coevolution and coalignment among a changing environment, transitional institutions, strategic adaptations, and performance implications. To revitalize this coevolutionary perspective in business ethics research, in this special issue, we ask the following question: how do business ethics practices coevolve with a changing society and technology advancement as a result of…Read more
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11Neural Activity Is Dynamically Modulated by Memory Load During the Maintenance of Spatial ObjectsFrontiers in Psychology 9. 2018.
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1We present VLT FORS1 and FORS2 spectra of 39 candidate high-redshift supernovae that were discovered as part of a cosmological study using type la supernovae over a wide range of redshifts. From the spectra alone, 20 candidates are spectrally classified as SNe Ia with redshifts ranging from z = 0.212 to z = 1.181. Of the remaining 19 candidates, 1 might be a type II supernova and 11 exhibit broad supernova-like spectral features and/or have supernova-like light curves. The candidates were discov…Read more
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© 2015 The Authors. Published by Oxford University Press on behalf of the Royal Astronomical Society.We use observedUVthrough near-IR spectra to examine whether SN 2011fe can be understood in the framework of Branch-normal Type Ia supernovae and to examine its individual peculiarities. As a benchmark, we use a delayed-detonationmodel with a progenitormetallicity of Z⊙/20. We study the sensitivity of features to variations in progenitor metallicity, the outer density profile, and the distribution…Read more
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Granule-based modelsIn Enrique H. Ruspini, Piero Patrone Bonissone & Witold Pedrycz (eds.), Handbook of fuzzy computation, Institute of Physics. 1998.
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75MNC Strategic Responses to Ethical Pressure: An Institutional Logic PerspectiveJournal of Business Ethics 98 (3): 373-390. 2011.In this study, we aim to investigate how multinational corporations (MNCs) balance ethical pressures from both the home and host countries. Drawing on theories from institutional theory, international business, and business ethics, we build a theoretical framework to explain the ethical behavior of MNCs. We apply the institutional logic concept to examine how MNCs with established logics and principles that have grown in the home country respond to local ethical expectations in the host country.…Read more
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Chronology of the life writings of Mr. Wang ZhongwenChinese Literature and Philosophy of Communication 21 (1): 137-150. 2011.
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84The Long-Term Sustenance of Sustainability Practices in MNCs: A Dynamic Capabilities Perspective of the Role of R&D and Internationalization (review)Journal of Business Ethics 110 (2): 205-217. 2012.What allows MNCs to maintain their sustainability practices over the long-term? This is an important but under-examined question. To address this question, we investigate both the development and sustenance of sustainability practices. We use the dynamic capabilities perspective, rooted in resource-based view literature, as the theoretical basis. We argue that MNCs that simultaneously pursue both higher R&D intensity and higher internationalization are more capable of developing and maintaining …Read more