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4923andMe: a new two-sided data-banking market modelBMC Medical Ethics 17 (1): 1-11. 2016.BackgroundSince 2006, the genetic testing company 23andMe has collected biological samples, self-reported information, and consent documents for biobanking and research from more than 1,000,000 individuals, through a direct-to-consumer online genetic-testing service providing a genetic ancestry report and a genetic health report. However, on November 22, 2013, the Food and Drug Administration halted the sale of genetic health testing, on the grounds that 23andMe was not acting in accordance with…Read more
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39Improving the Quality of Host Country Ethical Oversight of International Research: The Use of a Collaborative ‘Pre‐Review’ Mechanism for a Study of Fexinidazole for Human A frican TrypanosomiasisDeveloping World Bioethics 15 (3): 241-247. 2014.Developing countries face numerous barriers to conducting effective and efficient ethics reviews of international collaborative research. In addition to potentially overlooking important scientific and ethical considerations, inadequate or insufficiently trained ethics committees may insist on unwarranted changes to protocols that can impair a study's scientific or ethical validity. Moreover, poorly functioning review systems can impose substantial delays on the commencement of research, which n…Read more
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31Molecular Tumor Boards: Ethical Issues in the New Era of Data MedicineScience and Engineering Ethics 24 (1): 307-322. 2018.The practice and development of modern medicine requires large amounts of data, particularly in the domain of cancer. The future of personalized medicine lies neither with “genomic medicine” nor with “precision medicine”, but with “data medicine”. The establishment of this DM has required far-reaching changes, to establish four essential elements connecting patients and doctors: biobanks, databases, bioinformatic platforms and genomic platforms. The “transformation” of scientific research areas,…Read more
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22Molecular Tumor Boards: Ethical Issues in the New Era of Data MedicineScience and Engineering Ethics 24 (1): 307-322. 2018.The practice and development of modern medicine requires large amounts of data, particularly in the domain of cancer. The future of personalized medicine lies neither with “genomic medicine” nor with “precision medicine”, but with “data medicine”. The establishment of this DM has required far-reaching changes, to establish four essential elements connecting patients and doctors: biobanks, databases, bioinformatic platforms and genomic platforms. The “transformation” of scientific research areas,…Read more
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20Les limites de l’approche fondée sur le risque de la loi du 5 mars 2012 relative aux recherches impliquant la personne humaine, dite « loi Jardé » (review)Médecine et Droit 2019 (158): 118-129. 2019.
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16Systemic Modelling in BioethicsThe New Bioethics 26 (3): 197-209. 2020.Most human societies have undergone much greater change over the last few decades, or even years, than in the preceding millennia. This is partly due to the emergence of various phenomena in medici...
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12A qualitative study of professionals’ perspectives on the ethics of medically-delivered safer injection education for people who inject drugsBMC Medical Ethics 24 (1): 1-9. 2023.Background In this qualitative analysis we aimed to explore addiction physicians’ perspectives on safer injection education for people who inject drugs, especially: (1) on possible means of introducing safer injection education in the medical environment, (2) on the compatibility of safer injection education with each physician’s core values and goals, and (3) on possible reasons for the ethical dilemma in safer injection education. Methods We conducted semi-structured interviews with eleven phy…Read more
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9Facing new challenges to informed consent processes in the context of translational research: the case in CARPEM consortiumBMC Medical Ethics 22 (1): 1-13. 2021.BackgroundIn the context of translational research, researchers have increasingly been using biological samples and data in fundamental research phases. To explore informed consent practices, we conducted a retrospective study on informed consent documents that were used for CARPEM’s translational research programs. This review focused on detailing their form, their informational content, and the adequacy of these documents with the international ethical principles and participants’ rights.Metho…Read more
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6Entropy as the main justification for research in medical ethicsPhilosophy, Ethics, and Humanities in Medicine 17 (1): 1-2. 2022.Ethics is an unconventional field of research for a surgeon, as ethics in surgery owns several specificities and surgery is considered an aggressive specialty. Therefore, the interest of research in medical ethics is sometimes unclear.In this short essay, we discussed the interest of research in medical ethics using a comparison to thermodynamics and mainly, entropy. During the transformation of a figure from one state to another, some energy is released or absorbed; yet, a part of this energy i…Read more
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Autour de l’intégrité scientifique, la loyauté, et la probité: aspects clinique, éthiques et juridiques (edited book)Dalloz. 2016.