-
12Founding the Wnt gene family: How wingless was found to be a positional signal and oncogene homologBioessays 46 (2): 2300156. 2024.The Wnt family of developmental regulators were named after the Drosophila segmentation gene wingless and the murine proto‐oncogene int‐1. Homology between these two genes connected oncogenesis to cell‐cell signals in development. I review how wingless was initially characterized, and cloned, as part of the quest to identify developmental cell‐to‐cell signals, based on predictions of the Positional Information Model, and on the properties of homeotic and segmentation gene mutants. The requiremen…Read more
-
13Religion in the age of Constantine - (m.) Edwards religions of the Constantinian empire. Pp. XIV + 365. Oxford: Oxford university press, 2015. Cased, £30, us$49.50. Isbn: 978-0-19-968772-5 (review)The Classical Review 68 (1): 191-192. 2018.
-
10Size isn't everythingBioessays 25 (1): 5-8. 2003.Much progress has been made recently towards uncovering the mechanisms that control the size to which organisms and their organs grow, and identifying some of the genes responsible. Size control, however, is only half of the equation. In growing to the right size, tissues must also grow to the right shape. A recent paper1 suggests that a hitherto overlooked cellular behaviour governs the size and shape of a growing tissue, and issues a challenge to developmental biologists to identify the molecu…Read more
-
35Retinal determination genes function along with cell-cell signals to regulate Drosophila eye developmentBioessays 33 (7): 538-546. 2011.
Leeds, West Yorkshire, United Kingdom of Great Britain and Northern Ireland