Paul Smith

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:Being and Time. A Translation of “Sein und Zeit by Martin HeideggerP. Christopher SmithMartin Heidegger. Being and Time. A Translation of “Sein und Zeit. Translated by Joan Stambaugh. Albany: State University of New York Press, 1996. Pp. xix + 487. Paper, $18.95.A new English translation of Heidegger’s best book, Sein und Zeit has been eagerly anticipated ever since the appearance of the Macquarrie/Robinson translation in 1962.1 For anyone with an ear for German would find that, in turning Heidegger’s visceral prose into wooden terminology, this first pathbreaking and very scholarly translation failed completely to render the startling and wholly untraditional diction of this work, a diction that rocked a staid and stifling academia and that in lectures preceding the book’s publication had therefore attracted students in droves, among them Leo Strauss, Hanna Arendt, Hans-Georg Gadamer, Karl Löwith, Herbert Marcuse, and Hans Jonas. At long last, a new translation, Joan Stambaugh’s, is here, but, unfortunately, it is no better in this crucial regard, and it is not as scholarly either. (Macquarrie/Robinson do provide many detailed and useful accounts of their choices of translation.) Indeed, the new translation often seems to be a mere revision of the old and falls into much of the old translation’s terminological uprooting of Heidegger’s sometimes thick but always earthy language. Here are three examples.In S we find this rendering of Heidegger’s preliminary account of the phenomenological method he will apply in “laying out” our “factual” human existence “there” “in the world” of our cooperative taking care of life’s tasks:This “a priori” of the interpretation of Da-sein is not a structure which is pieced together, but rather a structure which is primordially and constantly whole. It grants various perspectives on the factors which constitute it. These factors are to be kept constantly in view, bearing in mind the preceding whole of this structure.(S 37)In M/R this same passage is translated, somewhat more readably and accurately, as:In the interpretation of Dasein, this structure is something ‘a priori’; it is not pieced together, but is primordially and constantly a whole. If affords us, however, various ways of looking at the items which are constitutive for it. The whole of this structure always comes first; but if we keep this constantly in view, these items, as phenomena, will be made to stand out.(M/R 65) [End Page 148]We note, first, how many of the M/R translations are taken over by S: “not a structure... pieced together,” which mistranslates “keine zusammengestückte Bestimmtheit” (SZ 41) or “not a determination arrived at bit by bit,” and “[structure]... primordial(ly) and constant(ly) (a) whole” for “eine ursprünglich und ständig ganze Struktur,” in which the English “primordial” turns the rather ordinary “ursprünglich” or “originally” into a technical term. Indeed, this phrase might best be rendered in more usual English along the lines of “This structure, assumed a priori... is originally, and continues to be, a whole.” For the point, lost in S but preserved in M/R with their “however,” is precisely that even though Dasein has been determined ahead of time to have the basic structure of a whole, we can still elucidate different sides of it phenomenologically by “throwing them into relief” (compare Heideger’s “phänomenal abzuheben”). In S, Heidegger’s pivotal “phänomenal” is lost altogether.Here, next, is how S renders Heidegger’s account of the call of conscience, which calls us back from our having lost ourselves in pressed busyness and vain chattering, at just that moment when these lose all their significance for us and go dead:The call is lacking any kind of utterance. It does not even come to words, and yet it is not at all obscure and indefinite. Conscience speaks solely and constantly in the mode of silence. Thus it not only loses none of its perceptibility, but forces Da-sein thus summoned and called upon to the reticence of itself.(S 252–53).And here is the M/R translation:The call dispenses with any kind of utterance. It does...

What, precisely, does the word hermeneutics mean? And in what sense can one speak of the hermeneutics of original argument? In _The Hermeneutics of Original Argument, _P. Christopher Smith explores these questions in building upon Heidegger's hermeneutical thought. In applying Heidegger's basic notion that hermeneutics is not a doctrine of interpretation but is its actual execution, Christopher Smith penetrates the abstractions that conceal original argument and explores the structure and nature of argument as it originally occurs.

In this international and interdisciplinary collection of critical essays, distinguished contributors examine a crucial premise of traditional readings of Plato's dialogues: that Plato's own doctrines and arguments can be read off the statements made in the dialogues by Socrates and other leading characters. The authors argue in general and with reference to specific dialogues, that no character should be taken to be Plato's mouthpiece. This is essential reading for students and scholars of Plato

Mesenchymal stem cells are capable of regenerative and immunomodulatory functions in cell-based therapies in a variety of human diseases and injuries; however, their therapeutic efficacy and potential side effects remain major obstacles in clinical applications. We report here a 3D spheroid culture approach to optimize stem cell properties and therapeutic effects of human gingiva-derived mesenchymal stem cells in mitigation of experimental oral mucositis. Under growth condition of ultra-low attachment, GMSCs spontaneously aggregated into 3D spheroids and exhibited distinct early stem cell phenotype characterized by elevated expression Stro-1 and CXC chemokine receptor 4 as well as OCT-4 and Nanog, 2 important transcriptional factors relevant to stem cell properties, and decreased expression of MSC-associated markers, including CD29, CD90, and CD105. Functionally, spheroid GMSCs are capable of enhanced multipotency and augmented secretion of several chemokines and cytokines relevant to cell migration, survival, and angiogenesis. More importantly, spheroid GMSCs expressed increased levels of reactive oxygen species, hypoxia-inducible factor -1 and -2α, and manganese superoxide dismutase, which correlated with improved resistance to oxidative stress-induced apoptosis. Using an in vivo murine model of chemotherapy-induced oral mucositis, we demonstrated that spheroid-derived GMSCs possessed better therapeutic efficacy than their adherent cells in reversing body weight loss and promoting the regeneration of disrupted epithelial lining of the mucositic tongues. These findings suggest that 3D spheroid culture allows early stemness preservation and potentially precondition GMSCs for enhanced mitigation of oral mucositis. © 2012 Mary Ann Liebert, Inc.