Qi Zeng

© 2015 Wiley Periodicals, Inc. Cell fragments devoid of the nucleus and major organelles are found in physiology and pathology, for example platelets derived from megakaryocytes, and cell fragments from white blood cells and glioma cells. Platelets exhibit active chemotaxis. Fragments from white blood cells display chemotaxis, phagocytosis, and bactericidal functions. Signaling mechanisms underlying migration of cell fragments are poorly understood. Here we used fish keratocyte fragments and demonstrated striking differences in signal transduction in migration of cell fragments and parental cells in a weak electric field. cAMP or cGMP agonists completely abolished directional migration of fragments, but had no effect on parental cells. The inhibition effects were prevented by pre-incubating with cAMP and cGMP antagonists. Blocking cAMP and cGMP downstream signaling by inhibition of PKA and PKG also recovered fragment galvanotaxis. Both perturbations confirmed that the inhibitory effect was mediated by cAMP or cGMP signaling. Inhibition of cathode signaling with PI3K inhibitor LY294002 also prevented the effects of cAMP or cGMP agonists. Our results suggest that cAMP and cGMP are essential for galvanotaxis of cell fragments, in contrast to the signaling mechanisms in parental cells.

In an increasingly competitive and performance-oriented society, workaholic leadership is becoming increasingly common and is even embraced and supported by many organizations. However, previous studies have not paid sufficient attention to the impact of workaholic leadership on employee psychology and behavior. This study, based on the conservation of resources theory, explores the effect of workaholic leadership on employee self-presentation. Through an empirical analysis of 256 employees’ questionnaires, we found a significant positive impact between workaholic leaders and employee self-presentation. This process was achieved through the partly mediating mechanisms of employee workplace anxiety. Concurrently, segmentation supplies negatively moderated the relationship between workplace anxiety and self-presentation and the overall mediating mechanism. These findings provide important insights into the underlying mechanisms of workaholic leadership and employee behavior, which can be utilized to improve employee wellbeing and provide positive organizational outcomes.

Enterprise Network has increasingly gained popularity in academia. Over the past few decades, a substantial amount of EN studies have been published in China. Drawing upon a sample of 603 papers retrieved from the Chinese Social Sciences Citation Index database between 1998 and 2020, this study aims to delve into the status quo, knowledge base, research focus, and evolutionary trends of EN research in China. A multifaceted bibliometric analysis was performed using CiteSpace. The findings mainly indicate that the research on EN in China has a clear development context, and the research content gradually changes from macro to micro. In addition to foreign Social Network theories, the research results of domestic scholars have become the basic knowledge in this field. The research includes these topics: the conceptualization of EN, EN as indicators of enterprise development, EN’s impact on start-ups, mechanisms of EN’s effect and governance of EN. The potential direction for future research has been identified as the integration between EN and other forms of networks, and the structure of EN.