Rajan Sharma

© 2014 Dmytrenko et al.Background: Symbioses between chemoautotrophic bacteria and marine invertebrates are rare examples of living systems that are virtually independent of photosynthetic primary production. These associations have evolved multiple times in marine habitats, such as deep-sea hydrothermal vents and reducing sediments, characterized by steep gradients of oxygen and reduced chemicals. Due to difficulties associated with maintaining these symbioses in the laboratory and culturing the symbiotic bacteria, studies of chemosynthetic symbioses rely heavily on culture independent methods. The symbiosis between the coastal bivalve, Solemya velum, and its intracellular symbiont is a model for chemosynthetic symbioses given its accessibility in intertidal environments and the ability to maintain it under laboratory conditions. To better understand this symbiosis, the genome of the S. velum endosymbiont was sequenced. Results: Relative to the genomes of obligate symbiotic bacteria, which commonly undergo erosion and reduction, the S. velum symbiont genome was large, GC-rich, and contained a large number of mobile genetic elements. Comparative genomics identified sets of genes specific to the chemosynthetic lifestyle and necessary to sustain the symbiosis. In addition, a number of inferred metabolic pathways and cellular processes, including heterotrophy, branched electron transport, and motility, suggested that besides the ability to function as an endosymbiont, the bacterium may have the capacity to live outside the host. Conclusions: The physiological dexterity indicated by the genome substantially improves our understanding of the genetic and metabolic capabilities of the S. velum symbiont and the breadth of niches the partners may inhabit during their lifecycle.

Since the very emergence of the syncretic, sentient human species, it has been handicapped by numerous incipient, continuing and new limitations. Thus, we have not yet quite escaped the overwhelming tyranny of biological evolution with its constraining strait jacket of natural selection. At this threshold of knowledge and awareness, the mantle falls on the Homo sapiens of planet Earth to at least dream of, and formulate prescriptions for Utopias without the inane internecine conflicts, and physical as well as spiritual carnages which continue unabated from the dawn of history to date, and which could now well aggravate towards inexorable total extinction. Channelisation of accumulated, collective wisdom, scienctific insights and technological skills towards universal humanistic rationality, emanicpation, and empowerment must be the primary edict of humankind. An equation incorporating Life, the human species, and various variables affecting these, is presented as a prescription for continuance and flowering of Life in the Universe

The genesis of God in human culture seems to be undeniably linked to fear of uncontrollable forces of Nature, and uncertanitity of individual destiny, which have been innate to the human ethos ever since the very emergence of modern man. Two opposite concepts of poly and monotheism, exemplified by Hinduism and Christianity, are analysed. Search for enduring and universal values and truisms through history of the two systems is deployed to identify commonalities. How far is plurality fissiparous, and partisan singularity unifying, is also compared. It is argued that progressive transcension must form the goal of all spiritual systems irrespective of regional or ethnic backrounds. Realities of the one world concept dictated by the inescapable Space ship Earth paradigm unequivocally lead to one species, one people, and one kind, hosowever anamolous the current trends. This inevitability must necessarily entail a unifying, single ethicality, with or without notion of Godhead. In essence, all spirituality stems from the need for individual or personal salvation and satisfaction. Group or species obligations come next, although it may be expected that with further human evolution these may supersede the selfish propensities predominant hitherto. It is emphasized that the evolutionarily transcendent human must suscribe to a universal ethical force which must necessarily belong to the genre of a singularity embracing the whole human kind. This could be called UNIETHICS, the epithet denoting the universal, the unitary and the unifying. Global consensus are tentatively emerging in several area, dictated by survival needs. Inviolable edicts of the now imperative UES or Uniethics have been spelled out, as also desiderata for achieving them