Samuela Marchiori

Considering public moral attitudes is a hallmark of the anticipatory governance of emerging biotechnologies, such as heritable human genome editing. However, such anticipatory governance often overlooks that future morality is open to change and that future generations may perform different moral assessments on the very biotechnologies we are trying to govern in the present. In this article, we identify an ’anticipatory gap’ that has not been sufficiently addressed in the discussion on the public governance of heritable genome editing, namely, uncertainty about the moral visions of future generations about the emerging applications that we are currently attempting to govern now. This paper motivates the relevance of this anticipatory gap, identifying the challenges it generates and offering various recommendations so that moral uncertainty does not lead to governance paralysis with regard to human germline genome editing.

Recent work on philosophy of technology emphasises the ways in which technology can disrupt our concepts and conceptual schemes. We analyse and challenge existing accounts of conceptual disruption, criticising views according to which conceptual disruption can be understood in terms of uncertainty for conceptual application, as well as views assuming all instances of conceptual disruption occur at the same level. We proceed to provide our own account of conceptual disruption as an interruption in the normal functioning of concepts and conceptual schemes. Moreover, we offer a multilevel taxonomy thereof, where we distinguish between instances of conceptual disruptions occurring at different levels (conceptual scheme, conceptual clusters, and individual concepts), taking on different forms (conceptual gaps and conceptual conflicts), and leading to different degrees of severity (extending from mild to severe). We also provide detailed accounts through historical examples of how conceptual gaps and conceptual conflicts can occur at different times in the very same process of conceptual disruption. Finally, we make the case that different kinds of conceptual engineering can provide meaningful ways to assess and overcome distinct types of conceptual disruption.