Sarah Gregory

Attentional scanning was studied in anxious and non-anxious participants, using a modified change detection paradigm. Participants detected changes in pairs of emotional scenes separated by two task irrelevant slides, which contained an emotionally valenced scene and a visual mask. In agreement with attentional control theory, change detection latencies were slower overall for anxious participants. Change detection in anxious, but not non-anxious, participants was influenced by the emotional valence and exposure duration of distractor scenes. When negative distractor scenes were presented at subliminal exposure durations, anxious participants detected changes more rapidly than when supraliminal negative scenes or subliminal positive scenes were presented. We propose that for anxious participants, subliminal presentation of emotionally negative distractor scenes stimulated attention into a dynamic state in the absence of attentional engagement. Presentation of the same scenes at longer exposure times was accompanied by conscious awareness, attentional engagement, and slower change detection

Background Men with antisocial personality disorder show lifelong abnormalities in adaptive decision making guided by the weighing up of reward and punishment information. Among men with antisocial personality disorder, modifi cation of the behaviour of those with additional diagnoses of psychopathy seems particularly resistant to punishment. Methods We did a case-control functional MRI (fMRI) study in 50 men, of whom 12 were violent off enders with antisocial personality disorder and psychopathy, 20 were violent off enders with antisocial personality disorder but not psychopathy, and 18 were healthy non-off enders. We used fMRI to measure brain activation associated with the representation of punishment or reward information during an event-related probabilistic response-reversal task, assessed with standard general linear-model-based analysis. Findings Offenders with antisocial personality disorder and psychopathy displayed discrete regions of increased activation in the posterior cingulate cortex and anterior insula in response to punished errors during the task reversal phase, and decreased activation to all correct rewarded responses in the superior temporal cortex. This finding was in contrast to results for off enders without psychopathy and healthy non-off enders. Interpretation Punishment prediction error signalling in off enders with antisocial personality disorder and psychopathy was highly atypical. This finding challenges the widely held view that such men are simply characterised by diminished neural sensitivity to punishment. Instead, this fi nding indicates altered organisation of the information processing system responsible for reinforcement learning and appropriate decision making. This difference between violent offenders with antisocial personality disorder with and without psychopathy has implications for the causes of these disorders and for treatment approaches.