•  4
    Background: The p53 tumor suppressor and its related protein, p73, share a homologous DNA binding domain, and mouse genetics studies have suggested that they have overlapping as well as distinct biological functions. Both p53 and p73 are activated by genotoxic stress to regulate an array of cellular responses. Previous studies have suggested that p53 and p73 independently activate the cellular apoptotic program in response to cytotoxic drugs. The goal of this study was to compare the promoter-bi…Read more
  •  5
    RNAa is a mechanism by which small dsRNA, termed saRNA, target promoter sequences to induce gene expression. This technique represents a novel approach to gene overexpression without the use of.
  • The Protein Ontology: A structured representation of protein forms and complexes
    with Darren Natale, A. Arighi, Cecilia N., Winona Barker, C. Blake, Judith A., Carol Bult, J. Caudy, Michael Drabkin, Harold J., Peter D’Eustachio, Alexei Evsikov, and Others Hongzhan
    Nucleic Acids Research 39 (suppl 1). 2011.