Xiao Liu

Sleep loss is associated with myriad decrements in cognitive function and is a ubiquitous risk factor for mood disorders. Nevertheless, little is known about the relations between sleep loss and its recovery and interference control of affective material. Delineating the association between interference control and sleep changes can provide insight into the link between sleep and the maintenance of mood disorders. Thus, the current study examined whether stimulus valence and time of day moderated the association between recovery sleep and cognitive inhibition following partial sleep deprivation. Healthy adults (N = 24) participated in a laboratory-based sleep study with baseline, sleep restriction, and recovery phases. Participants completed the modified Sternberg Task in the morning and afternoon on the final day of each phase. The association between recovery sleep and cognitive inhibition depended on time of day. Additionally, interference control improved from the baseline to the recovery phase, but not the sleep restriction phase, indicating that sleep deprivation may be associated with worse performance. The current study provides additional insight into factors (sleep and time of day) that are associated with interference control of affective information, which might have important implications for cognitive and emotional functioning.

Peirce's linear versions of the language of his Existential Graphs (EGs), presented in 1902, are examined. Differences between linear and non-linear languages are explained by permutational invariance and type- vs. occurrence-referentiality: Standard EGs are permutationally invariant with respect to linear EGs, while the Beta part of the system, which corresponds to first-order quantificational theory with identity, is occurrence-referential. However, occurrence-referentiality of Beta graphs constitutes a defect of expressivity: Since the meaning of a quantifier is inextricably connected to the meaning of the sign of identity, certain complex assertions cannot be expressed in the language of Beta graphs without a new extension of its standard notation. © 2021 Elsevier B.V., All rights reserved.

Improved tools for providing specific intraoperative diagnoses could improve patient care. In neurosurgery, intraoperatively differentiating non-operative lesions such as CNS B-cell lymphoma from operative lesions can be challenging, often necessitating immunohistochemical procedures which require up to 24-48 hours. Here, we evaluate the feasibility of generating rapid ex vivo specific labeling using a novel lymphoma-specific fluorescent switchable aptamer. Our B-cell lymphoma-specific switchable aptamer produced only low-level fluorescence in its unbound conformation and generated an 8-fold increase in fluorescence once bound to its target on CD20-positive lymphoma cells. The aptamer demonstrated strong binding to B-cell lymphoma cells within 15 minutes of incubation as observed by flow cytometry. We applied the switchable aptamer to ex vivo xenograft tissue harboring B-cell lymphoma and astrocytoma, and within one hour specific visual identification of lymphoma was routinely possible. In this proof-of-concept study in human cell culture and orthotopic xenografts, we conclude that a fluorescent switchable aptamer can provide rapid and specific labeling of B-cell lymphoma, and that developing aptamer-based labeling approaches could simplify tissue staining and drastically reduce time to histopathological diagnoses compared with IHC-based methods. We propose that switchable aptamers could enhance expeditious, accurate intraoperative decision-making.

Warning signs, as a type of safety signs, are widely applied in our daily lives to informing people about potential hazards and prompting safe behavior. Although previous studies have paid attention to the color of warning signs, they are mostly based on surveys and behavioral experiments. The neural substrates underlying the perception of warning signs with different background colors remain not clearly characterized. Therefore, this research is intended to address this gap with event-related potentials technique. Warning signs with three different background colors were used in the experiment. The results showed that the perceptual differences between different warning signs were present in the form of differential ERPs components though subjects were not required to explicitly attend to the warning signs.

Concentrating on the Qingdao Observatory, this paper will explore the role of scientific facility in asserting China’s sovereignty during the first half of the twentieth century. Although scholars have explained the efforts of China’s internationalization in diplomacy through the perspectives of politics, economics and culture, they have not paid attention to science. Therefore, this paper aims to shed some light on how scientific issues were solved via diplomacy during the Republic of China, while further asserting that the focus in negotiations was not confined to science itself, but rather to sovereignty within a scientific context. In this process, the meaning of sovereignty has also been expanded basing on the improvement of nation’s scientific capability. Besides, the participation of different actors involved in sovereignty assertion is investigated by this paper. Although the diplomatic negotiation was held at the international level, the local government and scientific community were main promoters in this case, which calls for attention on the various subjects in sovereignty issue. Consequently, this paper argues that Asian countries, such as Republic of China, could also employ science as a means to negotiate with foreign powers and claim their due rights.

The objectivity is a basic requirement for the measurements in the classical world, namely, different observers must reach a consensus on their measurement results, so that they believe that the object exists “objectively” since whoever measures it obtains the same result. We find that this simple requirement of objectivity indeed imposes an important constraint upon quantum measurements, i.e., if two or more observers could reach a consensus on their quantum measurement results, their measurement basis must be orthogonal vector sets. This naturally explains why quantum measurements are based on orthogonal vector basis, which is proposed as one of the axioms in textbooks of quantum mechanics. The role of the macroscopicality of the observers in an objective measurement is discussed, which supports the belief that macroscopicality is a characteristic of classicality.

The present study investigated the configuration effect of human capital, social capital, and psychological capital on job performance. The human capital questionnaire, social capital scale, psychological capital scale, and job performance scale were used to survey 458 employees. Results revealed that four antecedent configurations could achieve high task performance, and three antecedent configurations can achieve high contextual performance. The high job performance driving path was characterized by “all roads lead to Rome.” Human capital, social capital, and psychological capital affected job performance in the form of configuration, which reflected the asymmetric causal relationship.

The COVID-19 pandemic spread catastrophically over the world since the spring of 2020. In this paper, a heterogeneous branching process with immigration is established to quantify the human-to-human transmission of COVID-19 in local communities, based on the temporal and structural transmission patterns extracted from public case disclosures by four provincial Health Commissions in China. With proper parameter settings, our branching model matches the actual transmission chains satisfactorily and, therefore, sheds light on the underlying COVID-19 spreading mechanism. Moreover, based on our branching model, the efficacy of home quarantine and social distancing are explored, providing a reference for the effective prevention of COVID-19 worldwide.