Xiaowei Wang

A nonlinear coupled wing model subject to unknown external disturbances is proposed in this paper. Since the model is modeled by partial differential equations, the traditional control design scheme based on the ordinary differential equation model is not applicable, and the control law design becomes very complex. In this paper, a new antidisturbance boundary control scheme based on a finite time convergent disturbance observer is proposed. The control laws are designed based on the new disturbance observers to make the external disturbance errors converge to zero in a finite time and ensure the uniformly bounded stability of the controlled system. Finally, the effectiveness of the controllers and the finite-time convergence of disturbance errors are verified by the simulation and comparison.

Research has indicated that microRNAs (miRNAs), a special class of non-coding RNAs (ncRNAs), can perform important roles in different biological and pathological processes. miRNAs’ functions are realized by regulating their respective target genes (targets). It is thus critical to identify and analyze miRNA-target interactions for a better understanding and delineation of miRNAs’ functions. However, conventional knowledge discovery and acquisition methods have many limitations. Fortunately, semantic technologies that are based on domain ontologies can render great assistance in this regard. In our previous investigations, we developed a miRNA domain-specific application ontology, Ontology for MIcroRNA Target (OMIT), to provide the community with common data elements and data exchange standards in the miRNA research. This paper describes (1) our continuing efforts in the OMIT ontology development and (2) the application of the OMIT to enable a semantic approach for knowledge capture of miRNA-target interactions.

The writing of histories of Chinese philosophy in the first half of the twentieth century was pivotal in sustaining Chinese philosophy as a sub-discipline under philosophy. Feng Youlan's 馮友蘭 (1895–1990) two-volume _The History of Chinese Philosophy_ stands as a milestone contribution in the field of Chinese philosophy. However, the combined publication of the two volumes in 1934 overshadowed the publication of the first volume in 1931. The 1931 edition thus remains largely overlooked in the field of Chinese philosophy. In this article, I take Feng's discussion of the pre-Qin Yang Zhu as my focal point to examine the differences between the 1931 and 1934 editions, demonstrating how Feng's narration of Chinese philosophy was shaped by his engagement in the discourse on Chinese philosophy of his time and how his revised interpretation became definitive for the contemporary understanding of Yang Zhu.

In the 1920s, in the context of the New Culture movement, G u Jiegang 顧頡剛 (1893–1980) initiated the Chinese current of “Doubting Antiquity,” which aimed at a depolitization of ancient scholarship and a restoration of its historical value. During this process, Y ang Zhu 楊朱 (allegedly around 400 BCE) entered Gu’s discussion and became an integral part of Gu’s reconstruction of the Daoist tradition. In Gu’s understanding, the master Y ang Zhu had long been seriously misunderstood and wrongly interpreted. In the context of the Doubting Antiquity movement, Gu’s specific methodology, which insists on the validity of textual sources and a meticulous study of related expressions and ideas in different texts, enables him to not only offer an interpretation of Y ang Zhu that stands out from all modern reconstructions, but also to reconstruct and redefine a Daoist lineage that originated from Y ang Zhu’s thought. This essay is divided into two parts. In the first part (Section 2), I present how Gu manages to include a variety of ancient sources in his discussion of Y ang Zhu and how he reinterprets Y ang Zhu’s theory. In the second part (Section 3), I demonstrate how he places Y ang Zhu in a network of lineages and connections, hence associating him with a philosophy that centered on the discussion of human nature.

Technology is increasingly prominent as a topic of philosophical and normative reflection, as recent technological advancements in areas such as artificial intelligence and climate technologies have demonstrated their capability to disrupt our existing social, political, and moral practices. Recently, there is a call to diversify philosophy of technology, a field which has so far largely failed to engage with philosophical traditions outside the United States and Europe. While there are an increasing number of works that have attempted to answer the call, they are primarily attempts to apply normative values and/or frameworks of specific philosophical and cultural traditions. These works have not delved extensively into the questions of technology in these philosophical and cultural traditions; in particular, they have yet to explore how these philosophical and cultural traditions conceive and construct human-technology relations, namely how humans and technology are—and should be—related. This essay distinguishes itself from other attempts to apply normative values and/or frameworks of specific philosophical and cultural traditions. Our aim is to offer a Confucian view of human-technology relations through reviving three Confucian ideas in early Confucianism, namely Creating Qi from the Images (zhi qi shang xiang 制器尚象), Evoking Moral Feelings through Things (yi gu xing wu 以故興物), and Embedding the Rites into Qi (cang li yu qi 藏禮於器). Constructing human-technology relations in the Confucian perspective will offer us an account of how Confucianism sees technology (co-)shaping our perception of and action in the world; it can also provide us with alternative ways to consider technology’s normative implications.

This article discusses a Confucian notion of cosmological life and its eco-philosophical implication. In contrast to the Kantian notion of the man who has exclusive moral worth, existing as the ultimate value-conferrer among beings, Confucian cosmological man understands his/her selfness through the lens of sacred unity with other beings. The modern ecological disaster is arguably caused by the reluctance to recognize the inherent value of nature, which is due to the anthropocentrism partly introduced by the enlightenment notion of humanity. The Confucian cosmological person worships the ultimate value of the cosmos as a unity of heaven, humans, and earth, and in so doing delivers genuine care for the environment, not for the sake of its instrumental but for its inherent value.

In this paper, I discussed the possibility to argue for a human right to internet access in Confucian society. I argued firstly that Confucianism could properly accommodate the concept of human rights, even though it does not have an explicit term for it. Secondly, Confucian concept of min xin, as a similar concept of democracy with differences, is used in Confucianism as a normative concept to lay the foundation of the state and legitimatize the governance. Last but not least, I argued that the roles that min xin are supposed to play in reality are never fully carried out due to the specific hierarchical information structure of Confucian society. I proposed that with internet, the concept of min xin would have to be able to play its roles properly. As such, the arguments that disregard internet access by referting to the protection of the Confucian values might not stand.

Physical contact between organelles are widespread, in part to facilitate the shuttling of protein and lipid cargoes for cellular homeostasis. How do protein‐protein and protein‐lipid interactions shape organelle subdomains that constitute contact sites? The endoplasmic reticulum (ER) forms extensive contacts with multiple organelles, including lipid droplets (LDs) that are central to cellular fat storage and mobilization. Here, we focus on ER‐LD contacts that are highlighted by the conserved protein seipin, which promotes LD biogenesis and expansion. Seipin is enriched in ER tubules that form cage‐like structures around a subset of LDs. Such enrichment is strongly dependent on polyunsaturated and cyclopropane fatty acids. Based on these findings, we speculate on molecular events that lead to the formation of seipin‐positive peri‐LD cages in which protein movement is restricted. We hypothesize that asymmetric distribution of specific phospholipids distinguishes cage membrane tubules from the bulk ER.