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    Genetic variability and diversity are the result of a mutation-selection balance that acts permanently within and between species. The presence of deleterious mutations is a necessary consequence of this process and thus the price paid by a species for its capacity for further evolution (Haldane 1937, Am Nat 71:337–349). Recent estimations of mutation rate in the human lineage has revived the debate as to whether the high number of deleterious mutations poses a severe problem for the future of…Read more
  •  19
    Information: a universal metaphor in natural and cultural sciences? (review)
    with Mathias Gutmann and Wolfgang Hesse
    Poiesis and Praxis 5 (3-4): 155-158. 2008.
    Information: a universal metaphor in natural and cultural sciences? Content Type Journal Article DOI 10.1007/s10202-008-0046-2 Authors Michael Bölker, Philipps-Universität Marburg Fachbereich 17: Biologie Karl-von-Frisch-Straße 8 35032 Marburg Germany Mathias Gutmann, Philipps-Universität Marburg Institut für Philosophie Wilhelm Röpke Str. 6B 35032 Marburg Germany Wolfgang Hesse, Philipps-Universität Marburg Fachbereich 12: Mathematik und Informatik Hans-Meerwein-Straße 35032 Marburg Germany Jou…Read more
  •  23
    Genetic “information” or the indomitability of a persisting scientific metaphor
    with Tareq Syed and Mathias Gutmann
    Poiesis and Praxis 5 (3-4): 193-209. 2008.
    In the history of genetics, the information-theoretical description of the gene, beginning in the early 1960s, had a significant effect on the concept of the gene. Information is a highly complex metaphor which is applicable in view of the description of substances, processes, and spatio-temporal organisation. Thus, information can be understood as a functional particle of many different language games (some of them belonging to subdisciplines of genetics, as the biochemical language game, some …Read more